peony and licorice side effects

Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. 1987;(10):46-48. View abstract. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. J Steroid Biochem Mol Biol 1994;49:81-5. View abstract. J Am Soc Nephrol 2002;13(1):191-196. View abstract. 1991;4(2):166-173. 2003;84(1):85-89. View abstract. NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Mechanism of anti-inflammatory action of glycyrrhizin: effect on neutrophil functions including reactive oxygen species generation. View abstract. The invention belongs to the field of biopesticides, and mainly discloses a nuisanceless biological compound pesticide and a preparation method thereof. [A plant extract and its modified preparation in functional dyspepsia. Eagon PK, Elm MS, Hunter DS, et al. Br Med J 1971;3(773):501-503. [Treatment of chronic hepatitis B. QJM 2011;104(12):1093-1095. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding. View abstract. J Pharmacol Exp Ther 2006;316:1369-77. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. View abstract. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Chin J Integr Med 2022. Taking too much licorice can cause high blood pressure. We could use compounds in these foods to . View abstract. Acta Endocrinol (Buchar) 2020;16(4):508-510. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. An Bras Dermatol 2010;85(5):613-620. View abstract. View abstract. View abstract. The yellow-brown thick-branched roots are used as medicine. No side effects or changes in liver function tests occurred during the study. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . View abstract. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Pharmazie 2010;65(8):624-8. 2010;33(2):321-324. B. Licorice-associated reversible cerebral vasoconstriction with PRES. Moghadamnia, A. View abstract. Fitoterapia 2006;77(7-8):613-614. A multicentre trial. View abstract. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Kraus SD, Kaminskis A. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). View abstract. Severe hypokalaemia with paralysis induced by small doses of liquorice. Neth J Med 2005;63:149-50. View abstract. View abstract. Bernardi, M., D'Intino, P. E., Trevisani, F., Cantelli-Forti, G., Raggi, M. A., Turchetto, E., and Gasbarrini, G. Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. View abstract. World J Gastroenterol 2005;11:2124-9. . Meng Xiangrui is an academic researcher. Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. View abstract. Sheehan MP, Atherton DJ. Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. Int Urol Nephrol. View abstract. Effects of chalcones isolated from licorice roots on leukotriene biosynthesis in human polymorphonuclear neutrophils. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Effect of shakuyaku-kanzoh-toh, a prescription composed of shakuyaku (Paeoniae Radix) and kanzoh (Glycyrrhizae Radix) on guinea pig ileum. Can J Cardiol 2009;25(10):e357-e358. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Health Care Women Int. View abstract. Ann Noninvasive Electrocardiol. Ital.J Neurol.Sci 1997;18(4):217-220. Hussain RM. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Arch Pharm Res 2003;26(10):832-839. View abstract. Iran J Pharm Res. View abstract. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Licorice reduces body fat mass in obese men and women. Some birth control pills contain estrogen. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. View abstract. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. 1988;8(11):660-2, 645. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Visavadiya, N. P. and Narasimhacharya, A. V. Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. Phytother Res 2008;22(6):709-724. This can increase the effects and side effects of corticosteroids. Farese RV Jr, Biglieri EG, Shackleton CH, et al. View abstract. Wu, T. H., Chiu, T. Y., Tsai, J. S., Chen, C. Y., Chen, L. C., and Yang, L. L. Effectiveness of Taiwanese traditional herbal diet for pain management in terminal cancer patients. Anonymous. View abstract. 1. View abstract. Cotterill, J. View abstract. Licorice might change how these pumps work and change how much medication stays in the body. View abstract. View abstract. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. View abstract. The biological compound pesticide is manufactured from the raw materials of Ailanthus altissima Swingle, Cyrtomium fortunei, geranium wilfordii, fructus forsythiae, Scutellaria baicalensis, gallnut, areca-nut, coconut shell, radix sophorae . Am J Psychiatry 1994;151:617-8. Phytother Res. [Severe hypokalemia after holidays return]. Licorice can cause serious side effects if you take too much of it or use it for too long. Clin Med (Lond) 2017;17(1):43-5. View abstract. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. View abstract. Complement Ther Clin Pract. View abstract. View abstract. Eur J Obstet Gynecol.Reprod Biol 2007;131(1):61-67. Medicinal uses of licorice through the millennia: the good and plenty of it. Hinoshita F, Ogura Y, Suzuki Y, et al. Da Nagao, Y., Sata, M., Suzuki, H., Tanikawa, K., Itoh, K., and Kameyama, T. Effectiveness of glycyrrhizin for oral lichen planus in patients with chronic HCV infection. May Harm Baby During Pregnancy. The treatment of human cancer with agents prepared from bovine cartilage. Jia, Y. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Mattarello MJ, Karbowiak I, Ermolao A, and et al. Select a condition to view a list of vitamins. Amato P, Christophe S, Mellon PL. View abstract. 2011;25(2):312-313. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. J Ethnopharmacol 2011;135(1):162-72. Madisch A, Melderis H, Mayr G, et al. No negative side effects. Man SC, Li XB, Wang HH, et al. View abstract. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Asian Medical Journal 1984;26(7):423-438. View abstract. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. Wang H, Dong L, Qu F, et al. Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest. View abstract. One of its most known effects is the induction of hypertension, and it can induce what appears to be pseudohyperaldosteronism, due to glycyrrhetinic acid, the main active component of the root. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Au, T. K., Lam, T. L., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. Braz J Infect Dis 2016;20(6):534-8. Immunopharmacology 1999;41(3):169-181. Alt Med Rev 2001;6:495-9. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. 2020;45(2):257-264. Agarwal, A., Gupta, D., Yadav, G., Goyal, P., Singh, P. K., and Singh, U. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. 5-10-2004;208(1):89-94. Ann Clin Biochem 2007;44(Pt 4):397-399. Hyodo T, Taira T, Kumakura M, et al. Fan ZJ, Liu JM, Li XX, et al. Altern Med Rev 1999;4(3):178-188. View abstract. The anti-estrogenic action of beta-glycyrrhetinic acid. Ann Pharmacother 2003;37(6):836-838. View abstract. Oral Dis 2012;18(1):32-39. Int J Environ Res Public Health 2021;19(1):242. Armanini D, De Palo CB, Mattarello MJ, et al. Z., Zhang, Y. Inflammopharmacology 2022;30(2):477-486. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. Planta Med 1991;57(2):119-121. View abstract. Okubo T, Nagai F, Seto T, et al. Mol.Nutr Food Res 2011;55(2):318-327. Cisplatin is used to treat cancer. B., and Zhang, Z. J. Information from this source is evidence-based and objective, and without commercial influence. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. View abstract. View abstract. Phytother Res 1988;2(3):140-145. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. Licorice root and white peony for PCOS. View abstract. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Nutr Res 2012;32(2):85-92. J Clin Psychopharmacol 1997;17(3):234-235. Kumada T, et al. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. View abstract. Yoshino T, Yanagawa T, Watanabe K. Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature review. Nephron 2002;90:240. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy Isr J Dent Sci 1989;2(3):153-157. View abstract. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Taking peony along with estrogen might increase the effects and side effects from estrogen. Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. View abstract. Z. Am J Chin Med 1996;24:165-8. Phytother Res 2012;26(9):1381-1384. Gupta D, Agrawal S, Sharma JP. Li G, Simmler C, Chen L, et al. Additional reporting by Meghan De Maria. Lee, S., Lim, J. M., Jin, M. H., Park, H. K., Lee, E. J., Kang, S., Kim, Y. S., and Cho, W. G. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin. Hypertension and the cortisol-cortisone shuttle. Licorice can decrease potassium levels. We currently have no information for PEONY overview. View abstract. View abstract. Treatment of functional dyspepsia with a herbal preparation. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. Report of a new case]. Microbiol Immunol 2000;44(9):799-804. View abstract. Licorice might decrease how well cisplatin works. Medicine (Baltimore) 2019;98(35):e16601. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. J Agric Food Chem 6-13-2007;55(12):4691-4697. . Licorice-induced hypermineralocorticoidism. Large amounts of licorice can decrease potassium levels in the body. Middle East J Anaesthesiol. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Evid Based Complement Alternat Med. All rights reserved. Aldosterone is a hormone that causes your body to retain salt (sodium) and lose potassium. View abstract. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. View abstract. A., Lee, S. H., and Lee, S. M. Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice. View abstract. 1991;78(1-2):1-6. Taking licorice and loop diuretics together might make potassium levels drop too low. Am J Respir.Cell Mol.Biol. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. View abstract. Chamberlain, J. J. and Abolnik, I. View abstract. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. J Telemed Telecare. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. View abstract. Kase Y, Saitoh K, Ishige A, et al. 2018;38(2):617-8. Clin Ther 1999;21(12):2080-2090. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. View abstract. Wu G, Wu N, Li T, et al. As I've all but cut out alcohol, I've tended to drink this tea before going to bed and sometimes during the day. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. 2019;35:329-41. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. Zhou Y, Jin L, Kong F, et al. J Pharm Pharmacol 2003;55:1275-82. View abstract. Lee, S. M., Li, M. L., Tse, Y. C., Leung, S. C., Lee, M. M., Tsui, S. K., Fung, K. P., Lee, C. Y., and Waye, M. M. Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. View abstract. Am J Chin Med 1992;20(3-4):313-317. J Pharmacobiodyn 1983;6:153-60. . Gut 1973;14(9):711-715. J Assoc Physicians India 1989;37(10):647. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Lancet 1990;335(8697):1060-3. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. View abstract. Licorice can be used orally with Peony to treat women with Polycystic Ovary Syndrom to increase fertility; it can also treat patients with abnormal Prolactin, muscle spasms, or to reduce the pain of cancer. J Intern Med 1999;245:307-10. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. Nippon Rinsho 1994;52:1817-22. View abstract. View abstract. Eur J Dermatol. Gulf J Oncolog 2021;1(37):42-47. View abstract. 17. View abstract. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? de Klerk GJ, Nieuwenhuis G, Beutler JJ. View abstract. Yamamoto, T., Hatanaka, M., Matsuda, J., Kadoya, H., Takahashi, A., Namba, T., Takeji, M., and Yamauchi, A. 2012;18(4):534-543. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. van Uum SH. October 15, 2021. J Clin Psychopharmacol 2008;28(3):264-370. View abstract. The dose of your warfarin might need to be changed. *. Epilepsy Res 2021;176:106735. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. 2020;247:112226. View abstract. N Engl J Med 1968;278(25):1381-1383. View abstract. Cancer 1997;79(8):1494-1500. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. Monitor your blood pressure closely. View abstract. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. 6. View abstract. Melzer J, Rosch W, Reichling J, et al. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in men by licorice. Zhang W, Dai SM. Lee YS, Lorenzo BJ, Koufis T, et al. Hypertension encephalopathy after liquorice ingestion. View abstract. This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects. View abstract. Cochrane Database Syst Rev 2004;4:CD002291. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. This could change the effects and side effects of these medications. View abstract. View abstract. J Peripher.Nerv.Syst. Front Psychiatry 2020;11:605949. Lapi F, Gallo E, Bernasconi S, et al. N Engl J Med 1990;322:850. Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. View abstract. Li C, Wang ZB. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. BMJ Case Rep. 2012 Oct 19;2012. Hypokalemic paralysis due to licorice consumption is extremely rare, with only 40 cases in the English literature describing paralysis secondary to exposure to licorice in candies, medications, chewing tobacco, and herbal preparations. View abstract. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Plant Description. Kim YR, Nam SH. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Nihon Jinzo Gakkai Shi 2010;52(1):80-85. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. ""- . Madisch A, Holtmann G, Mayr G, et al. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. Dying for a cup of tea. View abstract. Zhong Yao Cai 2000;23:557-60. . Med Princ Pract 2010;19(6):485-489. Jan. 13, 2020 Foods such as honey, licorice, oregano, and hot sauce have an antimicrobial effect and some of them trigger phage production in our gut. View abstract. Caradonna, P., Gentiloni, N., Servidei, S., Perrone, G. A., Greco, A. V., and Russo, M. A. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. The effect of dong quai on menopausal symptoms is unknown. Some research suggests that licorice extract may help kill bacteria in the mouth that cause tooth decay. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity.

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peony and licorice side effects